NH-bis-PEG2

• Description :

  NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH-bis-PEG2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• UNSPSC :

  12352203

• Hazard Statement :

  H315, H319

• Target :

  ADC Linker; PROTAC Linkers

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/nh-bis-peg2.html

• Purity :

  97.0

• Solubility :

  10 mM in DMSO

• Smiles :

  OCCOCCNCCOCCO

• Molecular Formula :

  C8H19NO4

• Molecular Weight :

  193.24

• Precautions :

  H315, H319

• References & Citations :

  [1]Brown A, et al. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Non-cleavable Linker; PEG Linkers

• CAS Number :

  [54384-47-3]