AMBP Microglobulin Alpha-1 Protein Human

• Description:

  Alpha 1-microglobulin (A1M) is an immunomodulatory protein with a broad spectrum of possible clinical applications and seems a promising marker for evaluation of tubular function.

• Synonyms:

  Alpha-1 Microglobulin; A1M

• Gene Name:

  AMBP

• UniProt:

  P02760

• Tissue Specificity:

  Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha- trypsin inhibitor is present in plasma and urine.

• Source:

  Purified from the urine of patients with chronic renal tubular proteinuria

• Purification:

  Greater than 96.0%.

• Form:

  Sterile Filtered Off-White lyophilized (freeze-dried) powder.

• Reconstitution:

  Use phosphate buffer, pH>7.0 containing 0.15M NaCl, is recommended.

• Function:

  Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

• Shipping Conditions:

  Available

• Storage Conditions:

  Human A1M although stable at room temperature for 3 weeks, should be stored between 2-8°C.

• Other Gene Names:

  Protein AMBP

• Subcellular Location:

  Secreted.