B-RAF (Phospho-Ser446) Colorimetric Cell-Based ELISA Kit

• Description:

  The B-RAF (Phospho-Ser446) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor B-RAF (Phospho-Ser446) protein expression profile in cells. The kit can be used for measuring the relative amounts of B-RAF (Phospho-Ser446) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on B-RAF (Phospho-Ser446) .

• Synonyms:

  Serine/threonine-protein kinase B-raf;2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1, RAFB1

• Gene Name:

  BRAF

• UniProt:

  P15056

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Brain and testis.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

• Molecular Weight:

  84437 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Serine/threonine-protein kinase B-raf

• Subcellular Location:

  Nucleus. Cytoplasm. Cell membrane. Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.