Human Prothrombin witout GLA Domain

• Description:

  Human Prothrombin witout GLA Domain_x000D_ Catalog number: B2013215_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 mg_x000D_ Molecular Weight or Concentration: na_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20° C_x000D_ Keywords: Human Prothrombin-gla domainless_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Winter WE, Flax SD, Harris NS. Coagulation Testing in the Core Laboratory Lab Med. 2017 Nov 8;48(4):295-313._x000D_ 2: Blostein MD, Rigby AC, Jacobs M, Furie B, Furie BC. The Gla domain of human prothrombin has a binding site for factor Va J Biol Chem. 2000 Dec 1;275(48):38120-6._x000D_ 3: Tokunaga F, Takeuchi S, Omura S, Arvan P, Koide T. Secretion, gamma-carboxylation, and endoplasmic reticulum-associated degradation of chimeras with mutually exchanged Gla domain between human protein C and prothrombin Thromb Res. 2000 Sep 1;99(5):511-21._x000D_ 4: Wu W, Bancroft JD, Suttie JW. Structural features of the kringle domain determine the intracellular degradation of under-gamma-carboxylated prothrombin: studies of chimeric rat/human prothrombin Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13654-60._x000D_ 5: Card DJ, Gorska R, Harrington DJ. Laboratory assessment of vitamin K status J Clin Pathol. 2020 Feb;73(2):70-75._x000D_ 6: Itoh S, Yokoyama R, Kamoshida G, Fujiwara T, Okada H, Takii T, Tsuji T, Fujii S, Hashizume H, Onozaki K. Staphylococcal superantigen-like protein 10 (SSL10) inhibits blood coagulation by binding to prothrombin and factor Xa via their γ-carboxyglutamic acid (Gla) domain J Biol Chem. 2013 Jul 26;288(30):21569-80._x000D_ 7: Soriano-Garcia M, Park CH, Tulinsky A, Ravichandran KG, Skrzypczak-Jankun E. Structure of Ca2+ prothrombin fragment 1 including the conformation of the Gla domain Biochemistry. 1989 Aug 22;28(17):6805-10._x000D_ 8: Qureshi SH, Yang L, Manithody C, Bae JS, Rezaie AR. Functional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein C Biochim Biophys Acta. 2008 Sep;1780(9):1080-6._x000D_ 9: Li L, Darden T, Hiskey R, Pedersen LG. Computational studies of human prothrombin fragment 1, the Gla domain of factor IX and several biological interesting mutants Haemostasis. 1996;26 Suppl 1:54-9._x000D_ 10: Uehara S, Gotoh K, Handa H, Honjo K, Hirayama A. Process of carboxylation of glutamic acid residues in the gla domain of human des-gamma-carboxyprothrombin Clin Chim Acta. 1999 Nov;289(1-2):33-44. _x000D_ _x000D_ Products Related to Human Prothrombin witout GLA Domain can be found at Proteins

• Short Description:

  Catalog Number: B2013215 (5 mg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5