Cystathionine-β-synthase, Recombinant

• Description:

  Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. CBS uses the cofactor pyridoxal- phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S- adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro- lyases, which cleave carbon- oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.

• CAS Number:

  9000-83-3

• Activity:

  150 U/mg protein

• Storage Conditions:

  The lyophilized powder should be stored at - 20°C where it is stable for up to several years. The solution could be stored at 4° C where it is stable for up to 1 year. Repeated freezing and thawing cycles of the reconstitute d solution is not recommended .