5-Propargylamino-3'-azidomethyl-dUTP (tristriethylamine)

• UNSPSC Description:

  5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 5 in patent document WO2004018497A2. It contains an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC)[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/5-propargylamino-3-azidomethyl-dutp-tristriethylamine.html

• Purity:

  98.96

• Solubility:

  H2O : 125 mg/mL (ultrasonic)

• Smiles:

  O=C1N([C@H]2C[C@H](OCN=[N+]=[N-])[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)C=C(C(N1)=O)C#CCN.CCN(CC)CC.CCN(CC)CC.CCN(CC)CC

• Molecular Weight:

  879.81

• References & Citations:

  [1]Milton J, et, al. Modified nucleotides for polynucleotide sequencing. WO2004018497A2.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported