DDR2-IN-1

• UNSPSC Description:

  DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1].

• Target Antigen:

  Discoidin Domain Receptor

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ddr2-in-1.html

• Purity:

  99.88

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=NC=CC(OC2=CC=C(CNC(NC3=CC(C)=C(Cl)C=C3OCCN(C)C)=O)C=C2C)=C1)NC

• Molecular Weight:

  526.03

• References & Citations:

  [1]Margarita Wucherer-Plietker, et al. Inhibiteurs de ddr2 pour le traitement de l'arthrose. Patent WO2014032755A2.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1573053-23-2