Fibroblast growth factor receptor 2 Antibody / FGFR2

Fibroblast growth factor receptor 2 Antibody / FGFR2

• Description: Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.
• UniProt: P21802
• Host: Rabbit
• Immunogen: E. coli-derived recombinant human protein (amino acids R22-T821) was used as the immunogen for the Fibroblast growth factor receptor 2 antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB, FACS, Direct ELISA
• Format: Antigen affinity purified
• Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Reconstitution: After reconstitution, the Fibroblast growth factor receptor 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
• Limitations: This Fibroblast growth factor receptor 2 antibody is available for research use only.