Phospho-NLRP3 (Ser295) Antibody

• Gene Name:

  [NLRP3]

• NCBI Gene ID:

  114548

• Reactivity:

  Human, Mouse
  Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (88%), Dog (100%)

• Storage Conditions:

  Store at -20 degree C. Stable for 12 months from date of receipt.

• Specificity:

  Phospho-NLRP3 (Ser295) Antibody detects endogenous levels of NLRP3 only when phosphorylated at Ser295.
  Tissue Specificity: Predominantly expressed in macrophages. Also expressed in dendritic cells, B- and T-cells (at protein level). Expressed in LPS-treated granulocytes, but not in resting cells (at protein level). Expression in monocytes is very weak (at protein level). Expressed in stratified non-keratinizing squamous epithelium, including oral, esophageal and ectocervical mucosa and in the Hassall's corpuscles in the thymus. Also, detected in the stratified epithelium covering the bladder and ureter (transitional mucosa) (at protein level). Expressed in lung epithelial cells (at protein level). Expressed in chondrocytes. Expressed at low levels in resting osteoblasts.

• Other Gene Names:

  [NLRP3; NLRP3; AII; AVP; FCU; MWS; FCAS; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; PYPAF1; AGTAVPRL; C1orf7; CIAS1; NALP3; PYPAF1; CLR1.1]

• Short Name:

  [NLRP3]

• Other Product Names:

  [NACHT, LRR and PYD domains-containing protein 3 isoform b; NACHT, LRR and PYD domains-containing protein 3; NACHT, LRR and PYD domains-containing protein 3; cryopyrin; caterpiller protein 1.1; PYRIN-containing APAF1-like protein 1; NACHT, LRR and PYD containing protein 3; cold autoinflammatory syndrome 1 protein; NACHT domain-, leucine-rich repeat-, and PYD-con; NLR family, pyrin domain containing 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1]

• NCBI GI Number:

  34878690

• NCBI Accession Number:

  NP_899632

• NCBI GB Accession Number:

  NM_183395.2

• Uniprot Accession Number:

  Q96P20

• CAS Number:

  9007-83-4