ABP 215

CAT:

804-HY-P99476-02

Size:

1 mg

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CAS Number: 1438851-35-4
UNSPSC Description: ABP 215 (Bevacizumab-awwb), a Bevacizumab (Bevacizumab (HY-P9906)) biosimilar, is a humanized IgG1 monoclonal antibody targeting VEGFA (VEGFR). ABP 215 has anticancer effects, and can be used metastatic colorectal cancer (mCRC) research[1][2].
Target Antigen: VEGFR
Type: Inhibitory Antibodies
Related Pathways: Protein Tyrosine Kinase/RTK
Applications: Cancer-Kinase/protease
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/abp-215.html
Solubility: 10 mM in DMSO
Smiles: [ABP 215]
References & Citations: [1]Neungseon Seo, et al. Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab. MAbs. 2018 May/Jun;10(4):678-691. |[2]Whitney Rhodes, et al. Real-world use of bevacizumab-awwb, a bevacizumab biosimilar, in US patients with metastatic colorectal cancer. Future Oncol. 2021 Dec;17(36):5119-5127.
Shipping Conditions: Room temperature
Clinical Information: Phase 3

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