ALDH3A1-IN-1

ALDH3A1-IN-1

• CAS Number: 1039855-56-5
• UNSPSC Description: ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with an IC50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination research with docetaxel[1].
• Target Antigen: Aldehyde Dehydrogenase (ALDH)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/aldh3a1-in-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=CC1=CC([N+]([O-])=O)=C(C=C1)N(CCC)CCC
• Molecular Weight: 250.29
• References & Citations: [1]Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported