PerCP/Cyanine5.5 Anti-Human CD57 Antibody[HI57a]

• Background:

  CD57, also known as TB01, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants) .

• Abbreviation:

  CD57

• Gene ID:

  27087

• UniProt:

  Q9P2W7

• Host:

  Mouse

• Reactivity:

  Human

• Target:

  HNK-1; NK-1; Leu-7

• Clonality:

  Monoclonal

• Clone:

  HI57a

• Conjugation:

  PerCP/Cyanine 5.5

• Applications:

  FCM

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Mouse IgM, κ