CD106/VCAM1 (Activated Endothelial Cell Marker)

• Gene Name:

  [VCAM1]

• NCBI Gene ID:

  7412

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.

• Other Gene Names:

  [VCAM1; VCAM1; CD106; INCAM-100; L1CAM; V-CAM 1; VCAM-1]

• Short Name:

  [CD106/VCAM1]

• Other Product Names:

  [Vascular cell adhesion protein 1; Vascular cell adhesion protein 1; vascular cell adhesion protein 1; vascular cell adhesion molecule 1; INCAM-100; CD_antigen: CD106]

• NCBI GI Number:

  137560

• NCBI Accession Number:

  P19320.1

• Uniprot Accession Number:

  P19320