GRP94/HSP90B1 (Endoplasmic Reticulum Marker)

• Gene Name:

  [HSP90B1]

• NCBI Gene ID:

  7184

• Reactivity:

  Human, Monkey, Horse, Cow, Sheep, Pig, Rabbit, Dog, Rat, Mouse, Hamster, Guinea Pig, Chicken, Xenopus laevis

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

• Other Gene Names:

  [HSP90B1; HSP90B1; ECGP; GP96; TRA1; GRP94; HEL35; HEL-S-125m; GRP94; TRA1; GRP-94]

• Short Name:

  [GRP94/HSP90B1]

• Other Product Names:

  [endoplasmin; Endoplasmin; endoplasmin; heat shock protein 90 beta family member 1; 94 kDa glucose-regulated protein; GRP-94; Heat shock protein 90 kDa beta member 1; Tumor rejection antigen 1; gp96 homolog]

• NCBI GI Number:

  4507677

• NCBI Accession Number:

  NP_003290.1

• NCBI GB Accession Number:

  NP_003290.1

• Uniprot Accession Number:

  P14625