CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors)

CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors)

• Gene Name: [KIT]
• NCBI Gene ID: 3815
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
• Other Gene Names: [KIT; KIT; PBT; SCFR; C-Kit; CD117; MASTC; SCFR; SCFR; PBT]
• Short Name: [CD117/c-Kit]
• Other Product Names: [mast/stem cell growth factor receptor Kit isoform 1; Mast/stem cell growth factor receptor Kit; mast/stem cell growth factor receptor Kit; KIT proto-oncogene, receptor tyrosine kinase; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog]
• NCBI GI Number: 4557695
• NCBI Accession Number: NP_000213.1
• NCBI GB Accession Number: NP_000213.1
• Uniprot Accession Number: P10721