Collagen VII

• Gene Name:

  [COL7A1]

• NCBI Gene ID:

  1294

• Reactivity:

  Human, Sheep, Goat, Horse, Guinea Pig, Cow

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes an epitope located on collagenase digested Type VII collagen (150kDa), i.e. the non-helical carboxyl terminal region of the dimer. Binding is localized at the inferior border of the lamina densa as demonstrated by immunoelectron microscopy. Type VII is also found in the retina, where its function is unknown. It interacts with Laminin 5 and Fibronectin. Collagen VII is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.

• Other Gene Names:

  [COL7A1; COL7A1; EBD1; EBR1; EBDCT; NDNC8; LC collagen]

• Short Name:

  [Collagen VII]

• Other Product Names:

  [collagen alpha-1(VII) chain; Collagen alpha-1(VII) chain; collagen alpha-1(VII) chain; collagen type VII alpha 1 chain; Long-chain collagen]

• NCBI GI Number:

  4502961

• NCBI Accession Number:

  NP_000085.1

• NCBI GB Accession Number:

  NP_000085.1

• Uniprot Accession Number:

  Q02388