Insulin-like Growth Factor-1 (IGF-1)

Insulin-like Growth Factor-1 (IGF-1)

• Gene Name: [IGF-1]
• NCBI Gene ID: 3479
• Reactivity: Human, Mouse, Rat, Rabbit. Others not known.
• Storage Conditions: Antibody without azide: Store at -20 to -80 degree C.
  Non-hazardous. No MSDS required.
• Specificity: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
• Other Gene Names: [IGF1; IGF1; IGF; MGF; IGFI; IGF-I; IBP1; IGF-I; MGF]
• Short Name: [Insulin-like Growth Factor-1 (IGF-1)]
• Other Product Names: [insulin-like growth factor I isoform 4 preproprotein; Insulin-like growth factor I; insulin-like growth factor I; insulin like growth factor 1; Mechano growth factor; MGF; Somatomedin-C]
• NCBI GI Number: 11024682
• NCBI Accession Number: NP_000609.1
• NCBI GB Accession Number: NM_000618.4
• Uniprot Accession Number: P05019