Staurosporine

• Background:

  Staurosporine is a broad spectrum protein kinase inhibitor with activities ranging from anti-fungal to anti-hypertensive (1). Staurosporine is a typical ATP-competitive kinase inhibitor that binds to many kinases with high affinity, but with little selectivity (2).

• Description:

  Protein kinase inhibitor

• Product Name Alternative:

  (2S,3R,4R,6R) -3-Methoxy-2-methyl-4- (methylamino) -29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  >98% (TLC) ; NMR (Conforms)

• Weight:

  0.00025

• Format:

  Pale Yellow Solid

• Solubility:

  Soluble to 50 mM in DMSO

• Molecular Formula:

  C28H26N4O3

• Molecular Weight:

  466.54

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Ruegg U.T., and Burgess G.M. (1989) Trends in Pharm Science. 10(6): 218-220. 2. Karaman M.W., et al. (2008) Nat. Biotechnol. 26(1): 127-132.

• CAS Number:

  62996-74-1