Metronidazole

• UNSPSC Description:

  Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections[1][2][3][4].

• Target Antigen:

  Antibiotic; Apoptosis; Bacterial; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Metronidazole.html

• Purity:

  99.99

• Solubility:

  DMSO : 35 mg/mL (ultrasonic;warming)|H2O : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  OCCN1C([N+]([O-])=O)=CN=C1C

• Molecular Weight:

  171.156

• References & Citations:

  [1]Scully BE. Metronidazole. Med Clin North Am. 1988 May;72(3):613-21. |[2]Dhurga DB, et al. Granular Formation during Apoptosis in Blastocystis sp. Exposed to Metronidazole (MTZ). PLoS One. 2016 Jul 29;11(7):e0155390.|[3]Chaturvedi S, et al. Mechanistic exploration of quercetin against metronidazole induced neurotoxicity in rats: Possible role of nitric oxide isoforms and inflammatory cytokines. Neurotoxicology. 2020 Jul;79:1-10.|[4]Manickam R, et al. Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism. Int J Mol Sci. 2018 Aug 16;19(8):2418.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Launched

• CAS Number:

  443-48-1