TRPM7 Polyclonal Antibody

CAT: 0749-ABP60769-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60769-01Size:30 µL
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Background
TRPM7 (Transient Receptor Potential Cation Channel Subfamily M Member 7) is a Protein Coding gene. Among its related pathways are TRP channels and Cellular senescence (KEGG) . TRPM7 belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by TRPM7 is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. TRPM7 may also be associated with defects of cardiac function.
Description
Rabbit Anti-TRPM7 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Transient receptor potential cation channel subfamily M member 7; Channel-kinase 1; Long transient receptor potential channel 7; LTrpC-7; LTrpC7
Gene ID
54822
Accession Number
Q96QT4
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human TRPM7 protein
Clonality
Polyclonal
Tag
TRPM7
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
205kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of TRPM7 protein
Observed Molecular Weight
205
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Transient receptor potential cation channel subfamily M member 7; Channel-kinase 1; Long transient receptor potential channel 7; LTrpC-7; LTrpC7
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q96QT4
Isotype
Rabbit IgG

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