CC14B Polyclonal Antibody

• Background:

  Cell Division Cycle 14B encoded by CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.

• Description:

  Rabbit Anti-CC14B Polyclonal Antibody

• Product Name Alternative:

  Dual specificity protein phosphatase CDC14B; CDC14 cell division cycle 14 homolog B

• Gene ID:

  8555

• Accession Number:

  O60729

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human CC14B protein

• Clonality:

  Polyclonal

• Tag:

  CC14B

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  54kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of CC14B protein

• Observed Molecular Weight:

  54

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Dual specificity protein phosphatase CDC14B; CDC14 cell division cycle 14 homolog B

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/O60729

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG