GCS-β-2 Polyclonal Antibody

CAT: 0749-ABP54692-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54692-01Size:30 µL
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Background
Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.
Description
Rabbit Anti-GCS-β-2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
Gene ID
2974
Accession Number
O75343
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human GCS-β-2
Clonality
Polyclonal
Tag
Guanylate cyclase soluble subunit beta-2
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GCS-β-2 Polyclonal Antibody detects endogenous levels of GCS-β-2 protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O75343
Isotype
Rabbit IgG

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