ERK1/2 Rabbit pAb

• Background:

  Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

• Description:

  Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

• UniProt:

  P27361/P28482

• Swiss Prot:

  P27361/P28482

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant Protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB, IHC

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1,000-2,000 IHC 1:50-100

• Molecular Weight:

  44,42kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  44,42kDa

• Fragment:

  IgG

• Subcellular Location:

  Nucleus

• Other Product Names:

  MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

• Gene ID (Human):

  5594/5595