AST 487

• Description:

  RET kinase inhibitor

• Product Name Alternative:

  1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea

• Sequence:

  NVP-AST 487

• Field of Research:

  Tyrosine Kinase FLT3

• Purity:

  0.9929

• Solubility:

  ≥26.5 mg/mL in DMSO; insoluble in H2O; ≥51.2 mg/mL in EtOH

• Smiles:

  CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F

• Molecular Formula:

  C26H30F3N7O2

• Molecular Weight:

  529.56

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  630124-46-8