Lumiracoxib

• UNSPSC Description:

  Lumiracoxib is a potent,selective and orally active COX-2 inhibitor with a Ki value of 0.06?μM[1]. Lumiracoxib acts as a nonselective NSAID with?anti-inflammatory, analgesic and antipyretic activities. Lumiracoxib can be used for osteoarthritis and bone cancer research[1][2].

• Target Antigen:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/lumiracoxib.html

• Smiles:

  O=C(O)CC1=CC(C)=CC=C1NC2=C(F)C=CC=C2Cl

• Molecular Weight:

  293.72

• References & Citations:

  [1]Ronald Esser, et al. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. Br J Pharmacol. 2005 Feb;144(4):538-50.|[2]Alyson Fox, et al. Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat. Pain

• Shipping Conditions:

  Room Temperature

• CAS Number:

  220991-20-8