Cleomiscosin A

• UNSPSC Description:

  Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages[1][2].

• Target Antigen:

  TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cleomiscosin-a.html

• Purity:

  99.15

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  COC1=CC(C=CC2=O)=C(O2)C3=C1O[C@H](C4=CC(OC)=C(O)C=C4)[C@@H](CO)O3

• Molecular Weight:

  386.35

• References & Citations:

  [1]Sharma S, et al. Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether. Eur J Med Chem. 2010;45(11):5150-5156.|[2]Ma M, et al. Zhongguo Zhong Yao Za Zhi. 2007;32(12):1175-1179.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  76948-72-6