2,5-Di-tert-butylhydroquinone

• UNSPSC Description:

  2,5-Di-tert-butylhydroquinone (DTBHQ), the indirect food additive, regulates the activity of 5-lipoxygenase as well as the activity of COX-2 (IC50=1.8 and 14.1 μM for 5-LO and COX-2, respectively) [1].

• Target Antigen:

  COX; Lipoxygenase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/2-5-di-tert-butylhydroquinone.html

• Purity:

  99.90

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC1=CC(C(C)(C)C)=C(O)C=C1C(C)(C)C

• Molecular Weight:

  222.328

• References & Citations:

  [1]Zsofia Kutil, et al. The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro. Food and Agricultural Immunology. Volume 26, 2015-Issue 4.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  No Development Reported

• CAS Number:

  88-58-4