Procyanidin A1

Procyanidin A1

• CAS Number: 103883-03-0
• UNSPSC Description: Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects[1].
• Target Antigen: PKC
• Type: Natural Products
• Related Pathways: Epigenetics;TGF-beta/Smad
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/procyanidin-a1.html
• Purity: 99.19
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O[C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=C4C(O[C@]5(C6=CC=C(O)C(O)=C6)OC7=CC(O)=CC(O)=C7[C@@]4([H])[C@H]5O)=CC(O)=C3C1
• Molecular Weight: 576.50
• References & Citations: [1]Tomochika K, et al. Effects of peanut-skin procyanidin A1 on degranulation of RBL-2H3 cells. Biosci Biotechnol Biochem. 2011;75(9):1644-8.|[2]Takano F, et al. Aqueous extract of peanut skin and its main constituent procyanidin A1 suppress serum IgE and IgG1 levels in mice-immunized with ovalbumin. Biol Pharm Bull. 2007 May;30(5):922-7.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported