Ciliary Neurotrophic Factor (Human)

• Description:

  Ciliary Neurotrophic Factor (Human)_x000D_ Catalog number: B2010348_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Ciliary Neurotrophic Factor (Human) expressed in HEK 293. This protein acts as a pluripotent neurotrophic factor with myotrophic activities as well as a myokine capable of modulating osteoblast function._x000D_ Storage: -20C_x000D_ Keywords: rHuCNTF; Ciliary Neurotrophic Factor_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Xu B, Xie X. Neurotrophic factor control of satiety and body weight. Nat Rev_x000D_ Neurosci. 2016 May;17(5):282-92._x000D_ _x000D_ 2: Duncan JL. Ciliary Neurotrophic Factor Treatment Improves Retinal Structure_x000D_ and Function in Macular Telangiectasia Type 2. Ophthalmology. 2019_x000D_ Apr;126(4):550-551._x000D_ _x000D_ 3: Bongioanni P, Reali C, Sogos V. Ciliary neurotrophic factor (CNTF) for_x000D_ amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst Rev._x000D_ 2004;(3):CD004302._x000D_ _x000D_ 4: Girotti M, Silva JD, George CM, Morilak DA. Ciliary neurotrophic_factor_x000D_ signaling in the rat orbitofrontal cortex ameliorates stress-induced deficits in_x000D_ reversal learning. Neuropharmacology. 2019 Dec 1;160:107791._x000D_ _x000D_ 5: Jia C, Brown RW, Malone HM, Burgess KC, Gill WD, Keasey MP, Hagg T. Ciliary_x000D_ neurotrophic_factor is a key sex-specific regulator of depressive-like behavior_x000D_ in mice. Psychoneuroendocrinology. 2019 Feb;100:96-105._x000D_ _x000D_ 6: Pasquin S, Sharma M, Gauchat JF. Ciliary neurotrophic_factor (CNTF): New_x000D_ facets of an old molecule for treating neurodegenerative and metabolic syndrome_x000D_ pathologies. Cytokine Growth Factor Rev. 2015 Oct;26(5):507-15._x000D_ _x000D_ 7: Duff E, Baile CA. Ciliary neurotrophic_factor: a role in obesity? Nutr Rev._x000D_ 2003 Dec;61(12):423-6._x000D_ _x000D_ 8: Bok D. Ciliary neurotrophic_factor therapy for inherited retinal diseases:_x000D_ pros and cons. Retina. 2005 Dec;25(8 Suppl):S27-S28._x000D_ _x000D_ 9: Ghasemi M, Alizadeh E, Saei Arezoumand K, Fallahi Motlagh B, Zarghami N._x000D_ Ciliary neurotrophic_factor (CNTF) delivery to retina: an overview of current_x000D_ research advancements. Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):1694-1707._x000D_ 10: Adler R. Ciliary neurotrophic factor as an injury factor. Curr Opin_x000D_ Neurobiol. 1993 Oct;3(5):785-9. _x000D_ _x000D_ Products Related to Ciliary Neurotrophic Factor (Human) : Proteins

• Short Description:

  Catalog Number: B2010348 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5