D- (-) -Pantolactone

• Description:

  D- (-) -Pantolactone is an important intermediate that can be used in the synthesis of other active compounds, such as the molluscicide Cyanolide A. D- (-) -Pantolactone is also a calibrant for circular dichroism (CD) [1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Biochemical Assay Reagents; Drug Intermediate; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pantolactone.html

• Concentration:

  10mM

• Purity:

  99.96

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1OCC (C) (C) [C@H]1O

• Molecular Formula:

  C6H10O3

• Molecular Weight:

  130.14

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [3]Fang H, et al. Synthesis, biological activities, and docking studies of d-pantolactone derivatives as novel FAS inhibitors. Bioorg Med Chem. 2019 Oct 15;27 (20) :115069.|[1]Hajare AK, et al. Synthesis of molluscicidal agent cyanolide a macrolactone from D- (-) -pantolactone. J Org Chem. 2011 Feb 4;76 (3) :963-6.|[2]Konno T, et al. D-pantolactone as a circular dichromism (CD) calibration. Anal Biochem. 1975 Jul;67 (1) :226-32.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  599-04-2