Sunitinib malate

• Background:

  A potent inhibitor of multiple receptor tyrosine kinases including VEGFR, PDGFRβ and Kit (Ki = 2-17 nM) 1. Also inhibits cFMS (IC50=7 nM) 2 and FLT33. Potent inhibitor of angiogenesis4. Clinically useful anticancer agent. Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  Orange solid

• Storage Conditions:

  -20°C