JGB1741

• Description :

  JGB1741 is a potent and selective inhibitor of SIRT1 with an IC50 of 15 μM. JGB1741 modulates Bax/Bcl2 ratio, cytochrome c release and PARP cleavage and increases the acetylated p53 levels leading to p53-mediated apoptosis. JGB1741 can be used in studies about breast cancer.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  440.56

• Molecular Formula :

  C27H24N2O2S

• Notes :

  Research use only, not for human use.

• Receptor :

  Aurora B

• CAS Number :

  1256375-38-8