THBD Antibody (N-Term) [APR33526G]

• Background:

  Tissue Location: Endothelial cells are unique in synthesizing thrombomodulin

• Synonyms:

  Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM

• Gene Name:

  THBD

• Gene ID:

  7056

• UniProt:

  P07204

• Chromosomal Location:

  Membrane; Single-pass type I membrane protein.

• Applications:

  WB, FC, IF

• Dilution:

  IF--1:25 FC--1:25 WB--1:2000

• Function:

  Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

• Molecular Weight:

  60329

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality THBD Antibody (N-Term) [APR33526G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=7056

• Uniprot URL:

  https://www.uniprot.org/uniprot/P07204