ASGR2 Antibody (N-term) [APR33027G]

• Background:

  Tissue Location: Expressed exclusively in hepatic parenchymal cells.

• Synonyms:

  Asialoglycoprotein receptor 2, ASGP-R 2, ASGPR 2, C-type lectin domain family 4 member H2, Hepatic lectin H2, HL-2, ASGR2, CLEC4H2

• Gene Name:

  ASGR2

• Gene ID:

  433

• UniProt:

  P07307

• Chromosomal Location:

  Membrane; Single-pass type II membrane protein.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Function:

  Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N- acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

• Molecular Weight:

  35092

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ASGR2 Antibody (N-term) [APR33027G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=433

• Uniprot URL:

  https://www.uniprot.org/uniprot/P07307