BRCC3 Antibody (N-Term) [ApR04931G]

• Background:

  Tissue Location: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Aberrantly expressed in the vast majority of breast tumors.

• Synonyms:

  Lys-63-specific deubiquitinase BRCC36, 3419-, BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRISC complex subunit BRCC36, BRCC3, BRCC36, C61A, CXorf53

• Gene Name:

  BRCC3

• Gene ID:

  79184

• UniProt:

  P46736

• Chromosomal Location:

  Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole Note=Localizes at sites of DNA damage at double-strand breaks (DSBs) (PubMed:20656690, PubMed:26344097) . Interaction with ABRAXAS2 retains BRCC3 in the cytoplasm (PubMed:20656690) .

• Applications:

  WB

• Dilution:

  WB--1:2000

• Function:

  1921419320656690240759852634409720656690206566902407598526344097261956651921419326195665240759852634409724075985

• Molecular Weight:

  36072

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BRCC3 Antibody (N-Term) [ApR04931G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=79184

• Uniprot URL:

  https://www.uniprot.org/uniprot/P46736