Anti Mouse CCR8 mAb, Carrier-free (BSA/Glycerol-free)

• Background:

  Enables C-C chemokine receptor activity. Acts upstream of or within chemotaxis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and thymus primordium. Orthologous to human CCR8 (C-C motif chemokine receptor 8) .

• Synonyms:

  C-C; CCR-8; CKR-8; mCCR8; Cmkbr8; CC-CKR-8; C-C CKR-8

• Gene Name:

  Ccr8, Mus musculus (Mouse)

• UniProt:

  P56484

• Conjugation:

  Unconjugated

• Applications:

  Functional Assays

• Dilution:

  1:500-1:2000

• Form:

  Liquid

• Buffer:

  PBS, pH7.3, with 50% glycerol

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ccr8

• Overview:

  Regulatory T cells (Tregs) suppress host immune responses and maintain immune homeostasis. Tregs also promote cancer progression and participate in resistance to immune checkpoint inhibitor therapy. We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.

• Uniprot URL:

  https://www.uniprot.org/uniprotkb/P56484/entry

• Gene Name URL:

  https://www.ncbi.nlm.nih.gov/gene/12776