Human Recombinant IDO1

• Description:

  Human Recombinant IDO1 _x000D_ Catalog number: B2016936_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 25 µg_x000D_ Molecular Weight or Concentration: 46 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Indoleamine 2,3-dioxygenase 1, Indoleamine-pyrrole 2,3-dioxygenase_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Yang SL, Tan HX, Niu TT, Liu YK, Gu CJ, Li DJ, Li MQ, Wang HY. The IFN-γ-IDO1-kynureine pathway-induced autophagy in cervical cancer cell promotes phagocytosis of macrophage Int J Biol Sci. 2021 Jan 1;17(1):339-352._x000D_ 2: Saimi D, Wang Z, Zhu Q, Lv J. Expression, purification, and kinetic characterization of the human strep-IDO1 Transl Cancer Res. 2022 May;11(5):993-1004._x000D_ 3: Cheng AN, Cheng LC, Kuo CL, Lo YK, Chou HY, Chen CH, Wang YH, Chuang TH, Cheng SJ, Lee AY. Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles J Immunother Cancer. 2020 Dec;8(2):e001372._x000D_ 4: Bellucci M, Pompa A, De Marcos Lousa C, Panfili E, Orecchini E, Maricchiolo E, Fraternale D, Orabona C, De Marchis F, Pallotta MT. Human Indoleamine 2,3-dioxygenase 1 (IDO1) Expressed in Plant Cells Induces Kynurenine Production Int J Mol Sci. 2021 May 12;22(10):5102._x000D_ 5: Zheng Z, Guo X, Yu M, Wang X, Lu H, Li F, Wang J. Identification of Human IDO1 Enzyme Activity by Using Genetically Encoded Nitrotyrosine Chembiochem. 2020 Jun 2;21(11):1593-1596._x000D_ 6: Lee J, Jang J, Cha SR, Lee SB, Hong SH, Bae HS, Lee YJ, Yang SR. Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells Immune Netw. 2023 Dec 18;23(6):e48._x000D_ 7: Lou Q, Liu R, Yang X, Li W, Huang L, Wei L, Tan H, Xiang N, Chan K, Chen J, Liu H. miR-448 targets IDO1 and regulates CD8(+) T cell response in human colon cancer J Immunother Cancer. 2019 Aug 7;7(1):210._x000D_ 8: Tijono SM, Palmer BD, Tomek P, Flanagan JU, Henare K, Gamage S, Braun L, Ching LM. Evaluation of Novel Inhibitors of Tryptophan Dioxygenases for Enzyme and Species Selectivity Using Engineered Tumour Cell Lines Expressing Either Murine or Human IDO1 or TDO2 Pharmaceuticals (Basel). 2022 Aug 31;15(9):1090._x000D_ 9: Pol J, Bloy N, Buqué A, Eggermont A, Cremer I, Sautès-Fridman C, Galon J, Tartour E, Zitvogel L, Kroemer G, Galluzzi L. Trial Watch: Peptide-based anticancer vaccines Oncoimmunology. 2015 Jan 9;4(4):e974411._x000D_ 10: Arkhypov I, Özbay Kurt FG, Bitsch R, Novak D, Petrova V, Lasser S, Hielscher T, Groth C, Lepper A, Hu X, Li W, Utikal J, Altevogt P, Umansky V. HSP90α induces immunosuppressive myeloid cells in melanoma via TLR4 signaling J Immunother Cancer. 2022 Sep;10(9):e005551. _x000D_ _x000D_ Products Related to Human Recombinant IDO1 can be found at Proteins

• Short Description:

  Catalog Number: B2016936 (25 µg)_x000D_ Human Recombinant IDO1 is a high quality enzyme that catalyzes the first and rate-limiting step in the catabolism of the essential amino acid tryptophan. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3