Mouse Anti-Chicken CD8a-FITC

• NCBI Gene ID:

  677754

• Reactivity:

  Chicken

• Storage Conditions:

  The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 °C.

• Specificity:

  alpha chain of chicken CD8 (Mr 34 kDa)
  In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1,2 Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.3 MAb EP72 recognizes the CD8 alpha chain.

• Other Gene Names:

  [cd8a; cd8a; MGC136643; zgc:136643]

• Short Name:

  [CD8 alpha]

• Other Product Names:

  [CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide; CD8 alpha; CD8 antigen, alpha polypeptide]

• NCBI GI Number:

  91176308

• NCBI Accession Number:

  NP_001035138.1

• NCBI GB Accession Number:

  NM_001040049.1

• Uniprot Accession Number:

  Q24JW8

• CAS Number:

  9007-83-4