Rabbit anti Human Calcium Channel
CAT:
579-X1513P
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rabbit anti Human Calcium Channel
- Background: Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-ctx-GVIA) and omega-agatoxin-IVA (omega-aga-IVA).
- Synonyms: Voltage-Dependent L-Type Calcium Channel, β1 subunit
- CAS Number: 9007-83-4
- UniProt: Q02641
- Host: Rabbit
- Species Reactivity: Human
- Isotype: IgG
- Conjugation: Unconjugated
- Type: Polyclonal Antibody
- Applications: WB
- Field of Research: Signal Transduction
- Purification Method: Ammonium Sulfate Precipitation
- Assay Principle: This antibody can be used for Western blotting (5-10 µg/mL). Optimal concentration should be evaluated by serial dilutions.
- Stability: See expiration date on vial
- Concentration: See vial for Concentration
- Form: Provided as solution in phosphate buffered saline with 0,08% sodium azide
- Precautions: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
- References & Citations: 1. Powers, P.A., et al. 'Skeletal muscle and brain isoforms of a beta-subunit of Human voltage-dependent calcium channels are encoded by a single gene.' J. Biol. Chem. 1992, 267, 22967-22972. 2. Collin, T., et al. 'Molecular cloning of three isoforms of the L-type voltage-dependent calcium channel beta subunit form normal Human heart.' Circ. Res. 1993, 72, 1337-1344. 3. Fukuda, K., et al. 'Cyclic AMP-dependent modulation of N- and Q-type Ca2+ channels expressed in Xenopus oocytes.' Neurosci. Lett. 1996, 217, 13-16. 4. Hogan, K., et al. 'Structure and alternative splicing of the gene encoding the Human beta1 subunit of voltage dependent calcium channels.' Neurosci. Lett. 1999, 277, 111-114.
- Shipping Conditions: Ambient Temperature, freeze upon arrival
- Storage Conditions: Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
- Functional Analysis: WB