Desmoglein-3 (Squamous Cell Marker)

Desmoglein-3 (Squamous Cell Marker)

• Gene Name: [DSG3]
• NCBI Gene ID: 1830
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.
• Other Gene Names: [DSG3; DSG3; PVA; CDHF6; CDHF6; PVA]
• Short Name: [Desmoglein-3]
• Other Product Names: [desmoglein-3 preproprotein; Desmoglein-3; desmoglein-3; desmoglein 3; 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6]
• NCBI GI Number: 119964718
• NCBI Accession Number: NP_001935.2
• NCBI GB Accession Number: NM_001944.2
• Uniprot Accession Number: P32926