Catenin, beta (p120)

Catenin, beta (p120)

• Gene Name: [CTNNB1]
• NCBI Gene ID: 1499
• Reactivity: Human, Cow, Dog, Chicken. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb recognizes a protein of 92kDa, which is identified as beta-catenin. It shows no cross-reaction with gamma-catenin (also known as plakoglobin). The catenins, alpha, beta and gamma bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin was initially described as an E-cadherin-associated protein, and has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin has also been found in complexes with the tumor suppressor protein APC.
• Other Gene Names: [CTNNB1; CTNNB1; EVR7; CTNNB; MRD19; armadillo; CTNNB]
• Short Name: [Catenin, beta]
• Other Product Names: [catenin beta-1 isoform 1; Catenin beta-1; catenin beta-1; catenin beta 1; Beta-catenin]
• NCBI GI Number: 148233338
• NCBI Accession Number: NP_001091679.1
• NCBI GB Accession Number: NM_001098209.1
• Uniprot Accession Number: P35222