MUC5AC (Mucin 5AC / Gastric Mucin) Mouse Monoclonal Antibody

MUC5AC (Mucin 5AC / Gastric Mucin) Mouse Monoclonal Antibody

• CAS Number: 9007-83-4
• Gene Name: [MUC5AC]
• NCBI Gene ID: 4586
• Reactivity: Human
• Storage Conditions: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the N-terminal cysteine rich part of the peptide core of MUC5AC, which is heavily glycosylated. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. MAb 9-13M1 pairs with MAb 1-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
• Other Gene Names: [MUC5AC; MUC5AC; TBM; leB; MUC5; mucin; TBM]
• Short Name: [MUC5AC (Mucin 5AC / Gastric Mucin)]
• Other Product Names: [mucin-5AC; Mucin-5AC; mucin-5AC; mucin 5AC, oligomeric mucus/gel-forming; Gastric mucin]
• NCBI GI Number: 748983076
• NCBI Accession Number: NP_001291288.1
• NCBI GB Accession Number: NM_001304359.1
• Uniprot Accession Number: P98088