TGF-beta (Transforming Growth Factor beta) Mouse Monoclonal Antibody

• Gene Name:

  [TFGB]

• NCBI Gene ID:

  7040

• Reactivity:

  Human, Monkey, Cow, Dog, Mouse, Rat, Hamster

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This MAb recognizes TGF beta 1, 2 and 3. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFbeta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFbeta3 protein has approximately 80% identity to the mature region of both TGFbeta1 and TGFbeta2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFbeta's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.

• Other Gene Names:

  [TGFB1; TGFB1; CED; LAP; DPD1; TGFB; TGFbeta; TGFB; TGF-beta-1; LAP]

• Short Name:

  [TGF-beta (Transforming Growth Factor beta)]

• Other Product Names:

  [transforming growth factor beta-1 preproprotein; Transforming growth factor beta-1; transforming growth factor beta-1; transforming growth factor beta 1]

• NCBI GI Number:

  63025222

• NCBI Accession Number:

  NP_000651.3

• NCBI GB Accession Number:

  NM_000660.5

• Uniprot Accession Number:

  P01137

• CAS Number:

  9007-83-4