BCL10 (MALT-Lymphoma Marker) Mouse Monoclonal Antibody

• Gene Name:

  [BCL10]

• NCBI Gene ID:

  8915

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF-kB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

• Other Gene Names:

  [BCL10; BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10]

• Short Name:

  [BCL10]

• Other Product Names:

  [B-cell lymphoma/leukemia 10 isoform 1; B-cell lymphoma/leukemia 10; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10]

• NCBI GI Number:

  4502379

• NCBI Accession Number:

  NP_003912.1

• NCBI GB Accession Number:

  NM_003921.4

• Uniprot Accession Number:

  O95999

• CAS Number:

  9007-83-4