RABBIT ANTI CDKN2A

• Gene Name:

  [CDKN2A]

• NCBI Gene ID:

  1029

• Reactivity:

  Mouse, Rat

• Storage Conditions:

  Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  This item recognises human cyclin-dependent kinase inhibitor 2A (CDKN2A), a 16kDa protein belonging to the CDKN2 cyclin dependent kinase inhibitor family.
  
  CDKN2A acts as a negative regulator of cell proliferation by interacting strongly with CDK4 and CDK6, thus inhibiting their ability to interact with cyclin D and to phosphorylate the retinoblastoma protein.
  
  CDKN2A is an important tumour suppressor and defects in its production results in tumour formation in a wide range of tissues, including cutaneous malignant melanoma and Li-Fraumeni syndrome.

• Other Gene Names:

  [CDKN2A; CDKN2A; ARF; MLM; P14; P16; P19; CMM2; INK4; MTS1; TP16; CDK4I; CDKN2; INK4A; MTS-1; P14ARF; P19ARF; P16INK4; P16INK4A; P16-INK4A; CDKN2; MTS1; CDK4I; MTS-1; p16-INK4; p16INK4A]

• Short Name:

  [CDKN2A]

• Other Product Names:

  [cyclin-dependent kinase inhibitor 2A isoform p16INK4a; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3; cyclin-dependent kinase inhibitor 2A; CDK4 inhibitor p16-INK4; CDKN2A; cell cycle negative regulator beta; cyclin-dependent kinase 4 inhibitor A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); multiple tumor suppressor 1; cyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A]

• NCBI GI Number:

  4502749

• NCBI Accession Number:

  NP_000068.1

• NCBI GB Accession Number:

  NM_000077.4

• CAS Number:

  9007-83-4