NOX2/gp91phox Polyclonal Antibody

• Background:

  Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD) . In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

• Description:

  This is a NOX2/gp91phox Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, IMD34, NOX2, p91-PHOX, CYBB

• Gene ID:

  1536

• Swiss Prot:

  P04839

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human NOX2/gp91phox

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  65kDa/66kDa/67kDa

• Observed Molecular Weight:

  97-100KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG