Phospho-JAK3 (Tyr785) Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .

• Description:

  This is a Phospho-JAK3 (Tyr785) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  EC 2.7.10.2, JAK 3, JAK L, JAK-3, Jak3, JAK3 HUMAN, JAK3, JAKL, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3, Janus Kinase3, L JAK, L-JAK, Leukocyte janus kinase, LJAK, Protein tyrosine kinase leukocyte, Tyrosine protein kinase JAK3, Tyrosine-prote

• Swiss Prot:

  P52333

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Phospho-Specific Antibody

• Applications:

  WB, IHC-p, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  125 kDa

• Observed Molecular Weight:

  125 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG