Phospho-SMAD2/3 (Thr8) Polyclonal Antibody

• Background:

  SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF) -beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.

• Description:

  This is a Phospho-SMAD2/3 (Thr8) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SMAD2, MADH2, MADR2, Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD3, MADH3, Mothers against decapentaplegic

• Swiss Prot:

  Q15796, P84022

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human Smad2/3 around the phosphorylation site of Thr8

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Phospho-Specific Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, ELISA 1:10000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48 kDa

• Observed Molecular Weight:

  48 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG