MMP20 Polyclonal Antibody

• Background:

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.

• Description:

  This is a MMP20 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AI2A2, Enamel metalloproteinase, Enamelysin, Matrix metalloproteinase 20, Matrix metalloproteinase-20, MMP 20, MMP-20, MMP20, MMP20

• Swiss Prot:

  O60882

• Accession Number:

  NP_004762

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human MMP20

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  54 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG