PE/Cyanine7 Anti-Rat CD45 Antibody

• Background:

  CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

• Synonyms:

  Receptor-type tyrosine-protein phosphatase C,Leukocyte common antigen, LCA, T200, Ly-5,Ptprc

• Gene ID:

  19265

• Swiss Prot:

  P04157

• Host:

  Mouse

• Reactivity:

  Rat

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Conjugation:

  PE/Cyanine7

• Applications:

  FCM

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4